发明名称 |
Mesenchymal stem cells with increased developmental potency by expressing Nanog |
摘要 |
Disclosed herein are methods and materials for producing a more developmentally potent cell from a less developmentally potent cell. Specifically exemplified herein are methods that comprise introducing an expressible dedifferentiating polynucleotide sequence into a less developmentally potent cell, wherein the transfected less developmentally potent cell becomes a more developmentally potent cell capable of differentiating to a less developmentally potent cell of its lineage of origin or a different lineage.
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申请公布号 |
US8361791(B2) |
申请公布日期 |
2013.01.29 |
申请号 |
US201213483807 |
申请日期 |
2012.05.30 |
申请人 |
UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC.;SUGAYA KIMINOBU;ALVAREZ ANGEL |
发明人 |
SUGAYA KIMINOBU;ALVAREZ ANGEL |
分类号 |
C12N5/00;C12N5/02;C12N5/077 |
主分类号 |
C12N5/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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