发明名称 ANTIVIRAL AGENT - EYE DROPS
摘要 FIELD: medicine, pharmaceutics.SUBSTANCE: invention refers to medicine, particularly ophthalmology. Eye drops containing recombinant interferon stabilising the biological and physicochemical properties, stabilising resistance to microbial contamination, an antioxidant and a buffer mixture, contain antihistamine preparations specified in a group: antazoline, azelastin, tetryzoline, diphenhydramine hydrochloride as stabilising the biological and physicochemical properties, contains specified in the group: low-molecular polyvinylpyrrolidone, macrogol 400-12000, propylene glycol as stabilising resistance to microbial contamination contains specified in a group: Nipasol, sorbic acid, boric acid, besides it contains sodium chloride and/or sodium acetate in the following proportions in 1 ml of the solution. As an antioxidant, the eye drops contain disodium dihydrogen ethylenediaminetetraacetate and/or buthylhydroxytoluene in the amount of 0.0001-0.1 g in 1 ml of the solution. The eye drops contain recombinant interferon specified in a group: alpha-, beta-, gamma-interferon. As a buffer mixture, the eye drops contain borate-acetate or phosphate, or borate buffer.EFFECT: invention provides higher antiviral activity of the eye drops.4 cl, 5 ex
申请公布号 RU2473363(C1) 申请公布日期 2013.01.27
申请号 RU20120106474 申请日期 2012.02.24
申请人 MARKOV IL'JA ALEKSANDROVICH;MARKOVA ELENA ALEKSEEVNA;GAPONJUK POLINA PETROVNA;MARKOVA INNA NIKOLAEVNA 发明人 MARKOV IL'JA ALEKSANDROVICH;MARKOVA ELENA ALEKSEEVNA;GAPONJUK POLINA PETROVNA;MARKOVA INNA NIKOLAEVNA;GAPONJUK PETR JAKOVLEVICH
分类号 A61K38/21;A61P27/02 主分类号 A61K38/21
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