发明名称 |
VACCINE FOR CHIKUNGUNYA VIRUS INFECTION |
摘要 |
The present invention relates to vaccine formulation capable of eliciting protective immune response against Chikun-gunya virus infection in humans and other mammalian hosts. The immunogenic formulation comprises purified inactivated Chikun-gunya virus in a stable formulation. Methods of propagation and purification of the virus are discussed. The inactivated virus formulation is non-infectious, immunogenic and elicits protective immune response in mammalian host. The immunogenic composition is formulated for in vivo administration to humans. The invention also discusses the strategy of developing a subunit vaccine using the recombinant viral proteins as antigens for immunization. The recombinant virus antigens that are potentially immunogenic can be used in diagnosing for the presence of the virus.
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申请公布号 |
US2013022631(A1) |
申请公布日期 |
2013.01.24 |
申请号 |
US20070439509 |
申请日期 |
2007.08.31 |
申请人 |
ELLA KRISHNA MURTHY;SUMATHY KANDASWAMY;PYDIGUMMALA JAYA SHEELA;HEDGE NAGENDRA R. |
发明人 |
ELLA KRISHNA MURTHY;SUMATHY KANDASWAMY;PYDIGUMMALA JAYA SHEELA;HEDGE NAGENDRA R. |
分类号 |
A61K39/12;A61P31/14;C07K14/18;C12N7/00;C12N15/40;C12N15/63;C12N15/70;C12N15/74;C12N15/81;C12P21/02 |
主分类号 |
A61K39/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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