<p>Provided is an electron microscope on which can be mounted a high-voltage application specimen holder that takes into account operability while providing safety (a shock prevention mechanism). The present invention is characterized by being equipped with a specimen holder having a function whereby voltage is applied to a specimen stand on which a specimen is loaded, a voltage source that supplies the voltage applied to the specimen stand, and a voltage cable one end of which is connected to the specimen holder, with a relay device to which the other end of the voltage cable is connected being installed on a mount that supports the lens tube of the electron microscope.</p>