发明名称 TRPV4 ANTAGONISTS
摘要 <p>The present invention relates to spirocarbamate compounds of Formula (I) in which R1, (R2)Y, R3, R4, X and A have the meanings given in the specification. The invention further provides pharmaceutical compositions containing the compounds or pharmaceutically acceptable salts thereof and relates to their use of these compounds as TRPV4 antagonists in treating or preventing conditions associated with TRPV4 imbalance.</p>
申请公布号 CA2839743(A1) 申请公布日期 2013.01.24
申请号 CA20122839743 申请日期 2012.06.15
申请人 GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED 发明人 BROOKS, CARL;CHEUNG, MUI;EIDAM, HILARY SCHENCK;GOODMAN, KRISTA B.;HAMMOND, MARLYS;HILFIKER, MARK A.;HOANG, TRAM H.;PATTERSON, JACLYN R.;STOY, PATRICK;YE, GUOSEN
分类号 C07D263/52;C07D498/00 主分类号 C07D263/52
代理机构 代理人
主权项
地址