发明名称 1-(isoquinolin-1-yl)-4-(1-phenylmethyl) piperazines; dopamine receptor subtype specific ligands
摘要 Disclosed are compounds useful in treating psychotic disorders such as schizophrenia and other central nervous system diseases, where the compounds have general Formula I: wherein: Ar represents an aryl or heteroaryl group; R1 and R2 independently represent hydrogen, halogen, C1-C6 alkyl, C1-C4 alkoxy, C1-C4 alkylthio, hydroxy, amino, mono- or di(C1-C6)alkyl amino, cyano or trifluoromethyl; and R5 represents hydrogen or C1-C6 alkyl.
申请公布号 US6008352(A) 申请公布日期 1999.12.28
申请号 US19980034189 申请日期 1998.03.03
申请人 NEUROGEN CORPORATION 发明人 CHEN, XI
分类号 C07D217/22;C07D405/12;(IPC1-7):C07D401/04;C07D405/14 主分类号 C07D217/22
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