发明名称 |
3.4kb MITOCHONDRIAL DNA DELETION FOR USE IN THE DETECTION OF CANCER |
摘要 |
The present invention broadly claims a method for detecting cancer in an individual. The method comprises detecting a deletion in the nucleic acid sequence between residues 10743 and 12125 in mitochondrial DNA. The method comprises obtaining a biological sample from the individual; extracting the mitochondrial DNA (mtDNA) from the sample; quantifying the amount of mtDNA in the sample having a deletion in the nucleic acid sequence between residues 10743 and 14125 of the mtDNA genome; and comparing the amount of mtDNA in the sample having the deletion to at least one known reference sample.
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申请公布号 |
US2013022979(A1) |
申请公布日期 |
2013.01.24 |
申请号 |
US20100748120 |
申请日期 |
2010.03.26 |
申请人 |
GENESIS GENOMICS INC.;PARR RYAN;THAYER ROBERT;DAKUBO GABRIEL;CREED JENNIFER;ROBINSON KERRY;MAGGRAH ANDREA;REGULY BRIAN |
发明人 |
PARR RYAN;THAYER ROBERT;DAKUBO GABRIEL;CREED JENNIFER;ROBINSON KERRY;MAGGRAH ANDREA;REGULY BRIAN |
分类号 |
C12Q1/68 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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