摘要 |
<p>The present invention is directed to methods to detect and diagnose osteoporosis and periodontal disease using salivary biomarkers, wherein the biomarker is selected from the group consisting of osteocalcin, RANK L, soluble RANK L, osteoprotegerin, alkaline phosphatase, MIP 1 alpha, 1,25-dihyroxy Vitamin D, 25-Hydroxy Vitamin D, TRAP 5b, TRACP 5b, deoxypyridinoline, FGF-23, PTH, MMP 8, MMP 13, and alpha CTX-I.</p> |