Method for the early diagnosis of clinically latent placental insufficiency in placental dysmaturity

摘要

The present invention relates to a method for the early diagnosis of a clinically latent placental insufficiency in pathological placental dysmaturity, and the prophylaxis of intrauterine hypoxia/asphyxia at the due date or after a prolonged gestation, comprising determining the amount and/or the concentration of the biomarker prokineticin 1 (EG-VEGF) and/or its receptor PKR1 and/or PKR2 in a sample from the pregnant subject and/or the pregnancy.