A PREPARATION METHOD OF POROUS SCAFFOLDS OF CALCIUM PHOSPHATE CEMENT

摘要

PURPOSE: A manufacturing method of porous scaffolds is provided to manufacture porous scaffolds of calcium phosphate cement by injecting a suspension of the calcium phosphate cement and alginate into a mold filled with calcium ion aqueous solution, and to provide the effect of delivering biological molecules for stimulating bone reproduction by loading biological molecules for stimulating bone reproduction together in manufacturing the scaffolds. CONSTITUTION: A manufacturing method of porous scaffolds of calcium phosphate cement comprises the first step of making a suspension of calcium phosphate cement and alginate; and the second step of solidifying by injecting the suspension into a mold filled with calcium ion aqueous solution. The manufacturing method further includes a step of compressing the scaffolds mechanically after the second step. The mixing ratio of calcium phosphate cement to alginate is 20:1-500:1 based on the weight. The concentration of the calcium ion is 10-200 mM.