| 摘要 |
<p>Topical compositions for treatment of hyperpigmentation comprise an effective amount of S-acyl glutathione derivative and a carrier. Methods for treating hyperpigmentation, such as melasma, postinflammatory hyperpigmentation and lentigines, skin lightening and skin whitening comprise applying a composition containing S-acyl glutathione derivative in a dermatologically acceptable carrier to skin tissue. The acyl group is a saturated or unsaturated aliphatic C12-C24 group, preferably a C16-C24 group, most preferably a C16 group. In particularly preferred embodiments, the S-acyl glutathione derivative is S-palmitoyl glutathione.</p> |
