发明名称 |
DENDRITIC CELL MARKER AND USES THEREOF |
摘要 |
The present invention relates to the identification of proteins located on the cell surface of dendritic cells or precursors thereof, particularly antigen presenting dendritic cells. In particular, the present invention relates to compounds such as antibodies that bind these proteins. These compounds can be used to detect and/or enrich a subset of dendritic cells or precursors thereof. These compounds can also be used to target antigens to dendritic cells or precursors thereof to modulate a humoral and/or T cell mediated immune response to an antigen, or used to target cytotoxic agents to dendritic cells or precursors thereof involved in diseased states. |
申请公布号 |
EP2195346(A4) |
申请公布日期 |
2013.01.23 |
申请号 |
EP20080783037 |
申请日期 |
2008.08.29 |
申请人 |
THE WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH |
发明人 |
LAHOUD, MIREILLE HANNA;PROIETTO, ANNA IRENE;CAMINSCHI, IRINA;SHORTMAN, KEN;LEW, ANDREW MARK;WU, LI;WRIGHT, MARK DEXTER |
分类号 |
C07K16/28;C12N5/22;C12N15/09;G01N33/53 |
主分类号 |
C07K16/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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