发明名称 |
SUBSTUTED OXAZOLIDINONES AND THEIR USE IN THE FIELD OF BLOOD COAGULATON ABSTRACT |
摘要 |
N-oxazolidinylmethyl-substituted (benzo)thiophene carboxamides (I) and their salts, hydrates and prodrugs are new. - N-oxazolidinylmethyl-substituted (benzo)thiophene carboxamides of formula (I) and their salts, hydrates and prodrugs are new. - R1 = optionally benzo-fused thiophene, optionally substituted one or more times; - R2 = any selected organic group; - R3-R8 = same or different hydrogen or 1-6C alkyl. - Excluded are compounds where R2 = phenyl (optionally substituted once or more) and all of R3-R8 are hydrogen. - Independent claims are also included for the following: - (1) preparation of (I); and - (2) pharmaceutical composition containing (I), optionally also auxiliaries and carriers. - ACTIVITY - Anticoagulant; cardiant; anti-anginal; vasotropic; thrombolytic; cerebroprotective; antiarthritic; antiarteriosclerotic; cytostatic; nootropic; neuroprotective. - Test details are described but no results given. - MECHANISM OF ACTION - Coagulation factor Xa Inhibitor. |
申请公布号 |
HK1103235(A1) |
申请公布日期 |
2013.01.18 |
申请号 |
HK20070107638 |
申请日期 |
2007.07.17 |
申请人 |
BAYER SCHERING PHARMA AKTIENGESELLSCHAFT |
发明人 |
ALEXANDER STRAUB;THOMAS LAMPE;JENS POHLMANN;SUSANNE ROEHRIG;ELISABETH PERZBORN;KARL-HEINZ SCHLEMMER;JOSEPH PERNERSTORFER |
分类号 |
A61K;A61K31/42;A61K31/422;A61K31/423;A61K31/424;A61K31/427;A61K31/428;A61K31/4365;A61K31/444;A61K31/454;A61K31/496;A61K31/5355;A61K31/5377;A61K31/538;A61K31/5383;A61K31/541;A61P;A61P7/00;A61P7/02;A61P9/10;A61P19/02;A61P25/28;A61P35/00;A61P43/00;C07D;C07D413/12;C07D413/14;C07D417/14;C07D495/04;C07D498/04 |
主分类号 |
A61K |
代理机构 |
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代理人 |
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