发明名称 |
Process for selective derivatization of taxanes |
摘要 |
Processes for the preparation of taxol and other taxanes through selective derivatization of the C(7) and C(10) hydroxyl groups of 10-DAB, particularly a novel process using a new strategy in which the C(10) hydroxyl group is protected or derivatized prior to the C(7) hydroxyl group; and the provision of C(7) and C(10) derivatized 10-DAB compounds.
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申请公布号 |
US7288665(B1) |
申请公布日期 |
2007.10.30 |
申请号 |
US19980063477 |
申请日期 |
1998.04.20 |
申请人 |
FLORIDA STATE UNIVERSITY |
发明人 |
HOLTON ROBERT A.;ZHANG ZHUMING;CLARKE PAUL A. |
分类号 |
C07D305/14;C07D;C07F;C07F7/18 |
主分类号 |
C07D305/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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