| 发明名称 |
MODULATOR OF CELLULAR ADHESION |
| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide modulators of cellular adhesion. <P>SOLUTION: The present invention provides compounds having formula (I): and pharmaceutically acceptable derivatives thereof, and methods for the use thereof for the treatment of disorders mediated by the CD11/CD18 family of cellular adhesion molecules (e.g., LFA-1). The invention further provides methods for treating any disorder mediated through the CD11/CD18 family of cellular adhesion molecules, comprising a step of administering to a subject in need thereof a therapeutically effective amount of the compound. <P>COPYRIGHT: (C)2013,JPO&INPIT |
| 申请公布号 |
JP2013010778(A) |
申请公布日期 |
2013.01.17 |
| 申请号 |
JP20120191869 |
申请日期 |
2012.08.31 |
| 申请人 |
SARCODE BIOSCIENCE INC |
发明人 |
SHEN WANG;BARR KENNETH;OSLOB JOHAN D;ZHONG MIN |
| 分类号 |
C07D217/06;A61K31/40;A61K31/416;A61K31/47;A61K31/472;A61K31/4725;A61K31/502;A61K31/506;A61K31/517;A61K31/55;A61P1/04;A61P3/10;A61P5/14;A61P7/06;A61P9/08;A61P9/10;A61P11/00;A61P17/00;A61P17/02;A61P17/06;A61P21/00;A61P21/04;A61P25/00;A61P27/02;A61P29/00;A61P31/04;A61P37/02;A61P37/06;A61P37/08;A61P43/00;C07D231/56;C07D295/14;C07D401/06;C07D401/12;C07D401/14;C07D403/12;C07D403/14;C07D405/06;C07D405/12;C07D405/14;C07D407/14;C07D409/12;C07D409/14;C07D495/04 |
主分类号 |
C07D217/06 |
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