发明名称 |
METHODS AND COMPOSITIONS FOR ANTI-EGFR TREATMENT |
摘要 |
In some embodiments, the present invention provides methods for enhancing the sensitivity of cancer cells to anti-EGFR treatment, wherein the method comprises the introduction of a miR-200 miRNA to the cancer cells. In other embodiments, the present invention provides methods for treating cancer by exposing the cancer cells to an anti-EGFR composition after the above-mentioned enhancement step. In other embodiments, the present invention provides methods for assessing and enhancing the sensitivity of cancer cells to anti-EGFR treatment. In various other embodiments, the present invention provides compositions and expression vectors for practicing the afore-mentioned methods.
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申请公布号 |
US2013018088(A1) |
申请公布日期 |
2013.01.17 |
申请号 |
US201013504696 |
申请日期 |
2010.10.28 |
申请人 |
THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM;ADAM LIANA;DINNEY COLIN P.;MCCONKEY DAVID J. |
发明人 |
ADAM LIANA;DINNEY COLIN P.;MCCONKEY DAVID J. |
分类号 |
A61K48/00;A61P35/00;C12N15/85;C12Q1/68 |
主分类号 |
A61K48/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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