| 发明名称 |
Toll-Like Receptor Agonist Formulations and Their Use |
| 摘要 |
The present invention is directed generally to stable formulations of a TLR agonist preferably a TLR7 or a TLR8 agonist, for use in the treatment of cancer, preferably solid tumors and lymphomas. Specifically, the present invention is directed to stable formulations of up to 50 mg/ml of a TLR agonist which comprise a cyclodextrin.
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| 申请公布号 |
US2013018042(A1) |
申请公布日期 |
2013.01.17 |
| 申请号 |
US201213550192 |
申请日期 |
2012.07.16 |
| 申请人 |
HOWBERT J. JEFFRY;DUVVURI MURALIKRISHNA;HERSHBERG ROBERT;DIETSCH GREGORY |
发明人 |
HOWBERT J. JEFFRY;DUVVURI MURALIKRISHNA;HERSHBERG ROBERT;DIETSCH GREGORY |
| 分类号 |
A61K31/55;A61P17/00;A61P31/00;A61P35/00 |
主分类号 |
A61K31/55 |
| 代理机构 |
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