发明名称 4-OXO-3,5,7,8-TETRAHYDRO-4H-PYRANO {4,3-D} PYRMINIDINYL COMPOUNDS FOR USE AS TANKYRASE INHIBITORS
摘要 <p>The present invention provides for compounds of formula (I) wherein R1 and R2 are defined herein. The present invention also provides for pharmaceutical compositions and combinations comprising a compound of formula (I) as well as for the use of such compounds as tankyrase inhibitors and in the treatment of Wnt signaling and tankyrase 1 and 2 signaling related disorders which include, but are not limited to, cancer.</p>
申请公布号 WO2013010092(A1) 申请公布日期 2013.01.17
申请号 WO2012US46699 申请日期 2012.07.13
申请人 NOVARTIS AG;CHEUNG, ATWOOD, KIM;CHIN, DONOVAL, NOEL;FAN, JIANMEI;SHULTZ, MICHAEL, DAVID;TOMLINSON, RONALD, CHARLES 发明人 CHEUNG, ATWOOD, KIM;CHIN, DONOVAL, NOEL;FAN, JIANMEI;SHULTZ, MICHAEL, DAVID;TOMLINSON, RONALD, CHARLES
分类号 C07D491/052;A61K31/519;A61P35/00 主分类号 C07D491/052
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