| 发明名称 |
USE OF AN IL-6/IL-6 RECEPTOR COMPLEX FOR PREVENTING XEROSTOMIA INDUCED BY RADIOTHERAPY OR CHEMOTHERAPY |
| 摘要 |
<p>The present invention relates to methods for preventing or treating toxicities associated with exposure to ionizing radiation or to chemotherapy. Particularly, the present invention relates to methods for preventing or treating toxicities associated with radiation or chemotherapy comprising administering to a subject in need of such treatment polypeptide complexes comprising an IL-6 linked to a soluble IL-6 receptor, the polypeptide complexes capable of preventing or treating toxicities, particularly xerostomia.</p> |
| 申请公布号 |
EP2217264(B1) |
申请公布日期 |
2013.01.16 |
| 申请号 |
EP20080853559 |
申请日期 |
2008.11.27 |
| 申请人 |
HADASIT MEDICAL RESEARCH SERVICES AND DEVELOPMENTLTD. |
发明人 |
AXELROD, JONATHAN H.;GALUN, EITHAN;ROSE-JOHN, STEFAN;MARMARY, ITZHACK |
| 分类号 |
A61K38/20;A61K35/00;A61K38/17;A61K48/00;A61P1/00;C07K14/54 |
主分类号 |
A61K38/20 |
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