发明名称 |
GRAFT COPOLYMER WITH PH DEPENDENT BEHAVIOUR |
摘要 |
<p>A graft copolymer with pH dependent behavior of formula 1 Comprises, (i) a backbone having the formula 1 [A(X)B(Y)C(z)] wherein (A) is diol, (B) is dicarboxylic acid or acid anhydride and (C) is monomer containing pendent unsaturation such that (x)=41-45%, (y)=49-53% (z)=4-7% by mole; and (ii) a graft which is a polymer of the basic monomer (D) which comprises“w”weight percent of the total weight of said graft copolymer such that‘w’is 22-52%. The graft copolymers do not swell/dissolve at neutral and basic pH and swell/dissolve at acidic pH. The polymers are useful as protective coating for pharmaceutical dosage forms and as excipient in the development of extended release drug delivery systems.</p> |
申请公布号 |
EP2545089(A1) |
申请公布日期 |
2013.01.16 |
申请号 |
EP20110719897 |
申请日期 |
2011.03.09 |
申请人 |
COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH |
发明人 |
MUTHUSAMY, RAMESH;KULKARNI, MOHAN, GOPALKRISHNA |
分类号 |
C08F283/01;A61K47/34 |
主分类号 |
C08F283/01 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|