发明名称 |
MODIFIED FAMILY 5 CELLULASES AND USES THEREOF |
摘要 |
<p>The present invention relates to a modified Family 5 cellulase comprising a substitution of an amino acid at position 363 with a non-native alanine, serine or threonine, said position determined from alignment of the modified Family 5 cellulase with amino acids 71-397 of a Trichoderma reesei Cel5A amino acid sequence as set forth in SEQ ID NO:1 and enzyme mixtures comprising same. Additionally provided is a genetic construct comprising a nucleic acid sequence encoding the modified Family 5 cellulase and a genetically modified microbe comprising the genetic construct. The invention also provides a process for producing the modified Family 5 cellulase.</p> |
申请公布号 |
EP2545168(A1) |
申请公布日期 |
2013.01.16 |
申请号 |
EP20110752783 |
申请日期 |
2011.03.11 |
申请人 |
IOGEN BIO-PRODUCTS CORPORATION |
发明人 |
MASRI, NABIL;ST-PIERRE, PATRICK;MORTIMER, SANDRA;HILL, CHRIS |
分类号 |
C12N9/42;C11D3/386;C11D7/42;C12N15/56;C12N15/63;D06M16/00 |
主分类号 |
C12N9/42 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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