PYRIDINYL ACETONITRILES

摘要

The present invention is related to pyridinyl acetonitriles of formula (Ia), (Ib), and (Ic) (see formula Ia) (see formula Ib) (see formula Ic) as well as to pharmaceutical formulations containing such pyridinyl acetonitriles. Said pyridinyl acetonitriles are modulators of the protein kinase signaling pathways, particularly the one involving Glycogen Kinase Synthase 3 or JNK. The present invention is furthermore related to methods of preparing pyridinyl acetonitriles. X is a substituted or unsubstituted pyridinyl. G is an unsubstituted or substituted pyrimidinyl or triazinyl.