| 摘要 |
A recombinant or isolated integrin heterodimer comprising a novel subunit alpha10 in association with a subunit beta is described. The alpha10 integrin may be purified from bovine chondrocytes on a collagen-type-II affinity column. The integrin or the subunit of alpha10 can be used as a marker or target of all types of cells, e.g. of chondrocytes, osteoblasts, and fibroblasts. The integrin or the subunit alpha10 thereof can be used as a marker or target in different physiological or therapeutic methods. They can also be used as active ingredients in pharmaceutical compositions and vaccines. |
