发明名称 SHORT INTERFERING RIBONUCLEIC ACID (siRNA) FOR ORAL ADMINISTRATION
摘要 <P>PROBLEM TO BE SOLVED: To provide a short interfering ribonucleic acid (siRNA) for oral administration, the siRNA comprising two separate RNA strands that are complementary to each other over at least 15 nucleotides, wherein each strand is 49 nucleotides or less, and wherein at least one of which strands contains at least one chemical modification. <P>SOLUTION: The short interfering ribonucleic acid (siRNA) for oral administration, the siRNA comprising two separate RNA strands that are complementary to each other over at least 15 nucleotides, wherein each strand is 49 nucleotides or less, and wherein at least one of which strands contains at least one chemical modification, has been found out to be used for treating an angiogenesis disorder. <P>COPYRIGHT: (C)2013,JPO&INPIT
申请公布号 JP2013005812(A) 申请公布日期 2013.01.10
申请号 JP20120200083 申请日期 2012.09.12
申请人 NOVARTIS AG 发明人 NATT FRANCOIS JEAN-CHARLES;BILLY ERIC;HUNZIKER JUERG;SCHNELL CHRISTIAN RENE
分类号 C12N15/113;A61K9/08;A61K9/12;A61K31/713;A61K48/00;A61P1/16;A61P3/04;A61P5/14;A61P7/00;A61P9/10;A61P11/02;A61P11/06;A61P15/00;A61P17/00;A61P17/02;A61P19/02;A61P19/06;A61P19/08;A61P27/02;A61P29/00;A61P31/04;A61P35/00;A61P35/04;A61P37/08 主分类号 C12N15/113
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