摘要 |
<P>PROBLEM TO BE SOLVED: To provide a short interfering ribonucleic acid (siRNA) for oral administration, the siRNA comprising two separate RNA strands that are complementary to each other over at least 15 nucleotides, wherein each strand is 49 nucleotides or less, and wherein at least one of which strands contains at least one chemical modification. <P>SOLUTION: The short interfering ribonucleic acid (siRNA) for oral administration, the siRNA comprising two separate RNA strands that are complementary to each other over at least 15 nucleotides, wherein each strand is 49 nucleotides or less, and wherein at least one of which strands contains at least one chemical modification, has been found out to be used for treating an angiogenesis disorder. <P>COPYRIGHT: (C)2013,JPO&INPIT |