发明名称 |
Methods and Compositions for Nanoparticle-Mediated Cancer Cell-Targeted Delivery |
摘要 |
The present invention provides methods and compositions to selectively and directly deliver nanoparticles carrying an active agent to tumor cells. The active agent is internalized by the tumor cells, producing an anti-tumor effect for therapeutic applications and/or depositing a detectable marker for diagnostic applications. The present invention further provides a p53 chimera that circumvents the dominant negative activity of mutant p53 as a therapeutic in the treatment of cancer and reduction of mor size.
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申请公布号 |
US2013011333(A1) |
申请公布日期 |
2013.01.10 |
申请号 |
US201113522907 |
申请日期 |
2011.01.18 |
申请人 |
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM;YUAN ZHI-MIN;SEO SEOG-JIN |
发明人 |
YUAN ZHI-MIN;SEO SEOG-JIN |
分类号 |
A61K9/14;A61K31/7088;A61K38/02;A61K49/00;A61K51/04;A61K51/12;A61N5/10;A61P35/00;B82Y5/00;C12N5/071;C12Q1/02 |
主分类号 |
A61K9/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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