发明名称 ANTI-CANCER COMBINATIONS CONTAINING VEGF INHIBITOR AND IRINOTECAN
摘要 FIELD: medicine, pharmaceutics.SUBSTANCE: there are offered: an anti-cancer combination formed by VEGF Trap inhibitor with irinotecan and therapeutically applicable in treating neoplastic diseases, and a product containing it. What is shown is synergic action of the combination in growth inhibition of colonic carcinoma.EFFECT: invention enables using the ingredients of the combination in lower doses vs those applicable separately, and increasing activity with reduced toxicity or inhibiting their manifestations.3 cl, 1 tbl
申请公布号 RU2471483(C2) 申请公布日期 2013.01.10
申请号 RU20100103781 申请日期 2008.07.02
申请人 AVENTIS FARMA S.A. 发明人 BISSERI MARI-KRISTIN;SHIRON-BLONDEL' MARIELL';LEZHEN PASKAL';VRIN'O PATRIS'JA
分类号 A61K31/4745;A61K38/18;A61P35/00 主分类号 A61K31/4745
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