Functional-lipid constructs of the structure F-S-L are disclosed, wherein F comprises a tyrosine or histidine residue, S is a spacer covalently linking F to L and L is a lipid. The functional residue may be iodinated and used to radiolabel a biological entity with 1251 and the iodinated constructs are used in a non-invasive method of monitoring the distribution of a biological entity
申请公布号
AU2012226647(A1)
申请公布日期
2013.01.10
申请号
AU20120226647
申请日期
2012.02.09
申请人
HENRY, STEPHEN;KORCHAGINA, ELENA;TUZIKOV, ALEXANDER;RODIONOV, IGOR;BOVIN, NIKOLAI
发明人
BOVIN, NIKOLAI VLADIMIROVICH;HENRY, STEPHEN;KORCHAGINA, ELENA YURIEVNA;RODIONOV, IGOR LEONIDOVICH;TUZIKOV, ALEXANDER BORISOVICH