发明名称 |
RECOMBINANT PLASMID DNA pQE-60-TNFR-CrmB-Ind-67 AND pFastBac1-G2R-dSECRET CONTAINING SMALLPOX VIRUS GENOME FRAGMENT CODING TUMOUR NECROSIS FACTOR BINDING CrmB PROTEIN DOMAIN AND Bv/G2R-dSECRET BACULOVIRUS DOMAIN PRODUCING SECRETING TNF-BINDING CrmB PROTEIN OF SMALLPOX VIRUS WITH DELETED SECRET DOMAIN |
摘要 |
FIELD: medicine.SUBSTANCE: there are presented two recombinant plasmid DNA pFastBac 1 -G2R-dSECRET and pQE-60-TNFR-CrmB-Ind-67 coding TNF-binding CrmB protein domain. Said recombinant plasmid DNA pQE-60-TNFR-CrmB-Ind-67 is designed for transformation in cells of the strain E.coli SG13009[pRep4] - a producer of TNF-binding CrmB BHO protein domain.EFFECT: presented group of inventions is applicable for preparing drugs used in therapy of severe human diseases caused by hyperproduction of tumour necrosis factor and may be used in medicine.3 cl, 3 dwg, 12 ex |
申请公布号 |
RU2471869(C1) |
申请公布日期 |
2013.01.10 |
申请号 |
RU20110118764 |
申请日期 |
2011.05.10 |
申请人 |
FEDERAL'NOE BJUDZHETNOE UCHREZHDENIE NAUKI "GOSUDARSTVENNYJ NAUCHNYJ TSENTR VIRUSOLOGII I BIOTEKHNOLOGII "VEKTOR" (FBUN GNTS VB "VEKTOR") |
发明人 |
TREGUBCHAK TAT'JANA VLADIMIROVNA;NEPOMNJASHCHIKH TAT'JANA SERGEEVNA;ANTONETS DENIS VIKTOROVICH;SHCHELKUNOV SERGEJ NIKOLAEVICH |
分类号 |
C12N15/62;A61K38/16;C12N7/01;C12N15/28;C12N15/39;C12N15/86 |
主分类号 |
C12N15/62 |
代理机构 |
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代理人 |
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地址 |
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