摘要 |
<p>Vaccine comprising a peptide bound to a pharmaceutically acceptable carrier, said peptide having the amino acid sequence
(X<Sub>1</Sub>)<Sub>m</Sub> (X<Sub>2</Sub>)<Sub>n</Sub> (X<Sub>3</Sub>)<Sub>o</Sub> X<Sub>4</Sub> X<Sub>5</Sub> H P X<Sub>6</Sub> (Formula I),
for treating and/or preventing a physical disorder associated with the renin-activated angiotensin system, wherein
X<Sub>1</Sub> is D,
X<Sub>2</Sub> is A, P, M, or R,
X<Sub>3</Sub> is G, A, H, or V,
X<Sub>4</Sub> is Y,
X<Sub>5</Sub> is A, D, or I,
X<Sub>6</Sub> is F,
wherein mis independently 0 or 1 and n and o are 1, and wherein the peptide is not DRVYIHPF or RVYIHPF.</p> |