| 发明名称 |
Synthesis of UDP-glucose: N-acylsphingosine glucosyltransferase inhibitors |
| 摘要 |
Disclosed is a novel enantiomeric synthesis of ceramide-like inhibitors of UDP-glucose: N-acylsphingosine glucosyltransferase. Also disclosed are novel intermediates formed during the synthesis. |
| 申请公布号 |
EP2266968(B1) |
申请公布日期 |
2013.01.09 |
| 申请号 |
EP20100075429 |
申请日期 |
2002.07.16 |
| 申请人 |
GENZYME CORPORATION |
发明人 |
HIRTH, BRADFORD;SIEGEL, CRAIG |
| 分类号 |
C07D295/12;C07D295/185;A61K31/40;A61K31/4025;A61P1/16;A61P7/06;A61P17/02;A61P25/28;A61P27/02;A61P35/00;A61P43/00;C07B53/00;C07B61/00;C07D295/18;C07D319/18;C07D498/04 |
主分类号 |
C07D295/12 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
