发明名称 |
IL-6 DETECTION BASED EARLY DIAGNOSIS AND PREDICTION OF SYSTEMIC INFLAMMATORY RESPONSE SYNDROME AND SEPSIS IN ASYMPTOMATIC PATIENTS |
摘要 |
Methods, systems and kits for the early diagnosis or prediction of systemic inflammatory response syndrome (SIRS) including sepsis in asymptomatic patients, such as patients undergoing a surgical intervention, are provided. Some embodiments include a method and system for the detection or diagnosis of SIRS, or detection or diagnosis of a risk to suffer from or develop SIRS, in an asymptomatic patient comprising the steps of determining the level of IL-6 (or a variant thereof) in a sample from the patient; comparing the level of IL-6 (or a variant thereof) to a reference level; detecting or diagnosing SIRS or diagnosing a risk to suffer from or develop SIRS, wherein the sample is isolated at least 2 times at short intervals and the determining and comparing steps are both repeated for each sample. Also provided are methods, systems and kits for therapy monitoring and mortality prediction. |
申请公布号 |
EP2542894(A1) |
申请公布日期 |
2013.01.09 |
申请号 |
EP20110708189 |
申请日期 |
2011.03.02 |
申请人 |
ROCHE DIAGNOSTICS GMBH;F.HOFFMANN-LA ROCHE AG;MEDIZINISCHE UNIVERSITAET GRAZ |
发明人 |
GRUEB, SUSANNE;SMOLLE-JUETTNER, FREYJA-MARIA;NEUBOECK, NICOLE;WEINBERG, ANNELIE-MARTINA |
分类号 |
G01N33/68 |
主分类号 |
G01N33/68 |
代理机构 |
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