发明名称 |
DETECTION OF DNA METHYLATION |
摘要 |
<p>In a first aspect, the invention concerns a method for detecting or quantifying DNA methylation at a locus. In one embodiment, a methylation-sensitive endonuclease is formulated together with a polymerase enzyme in an appropriate reaction mixture such that amplification of DNA occurs in a methylation specific manor. Quantitative DNA amplification at selected loci can be used to determine the level of methylation. Kits and reagents for performing such methods are also provided.</p> |
申请公布号 |
EP2542698(A1) |
申请公布日期 |
2013.01.09 |
申请号 |
EP20110751298 |
申请日期 |
2011.03.02 |
申请人 |
ZYMO RESEARCH CORPORATION |
发明人 |
JIA, XIYU;CHIMA-OKEREKE, ONYINYECHI;NGUYEN, LAM |
分类号 |
C12Q1/68;C12P19/34 |
主分类号 |
C12Q1/68 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|