发明名称 |
PENTENOIC ACID DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF, PHARMACEUTICAL COMPOSITIONS COMPRISING THEM, AND THERAPEUTIC APPLICATIONS THEREOF |
摘要 |
The invention relates to compounds of the formula (I): (see formula I) in which R1 represents a(C6-C18)aryl radical substituted by and/or fused to a saturated or unsaturated 5- to 8-membered monocyclic or polycyclic nucleus optionally containing one or more hetero atoms chosen from O, N and S, the said nucleus itself being optionally substituted; R2 and R3 are a hydrogen atom or a (C6-C18)aryl radical; and R is a hydrogen atom or a C1-C10 alkyl radical; to their use for the treatment of dyslipidaemia, atherosclerosis and diabetes, to pharmaceutical compositions comprising them and to the processes for the preparation of these compounds.
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申请公布号 |
CA2566369(C) |
申请公布日期 |
2013.01.08 |
申请号 |
CA20052566369 |
申请日期 |
2005.04.06 |
申请人 |
MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG |
发明人 |
ZEILLER, JEAN JACQUES;DUMAS, HERVE;GUYARD-DANGREMONT, VALERIE;BERARD, ISABELLE;CONTARD, FRANCIS;GUERRIER, DANIEL;FERRAND, GERARD;BONHOMME, YVES |
分类号 |
C07C59/68;A61K31/192;A61K31/222;A61K31/381;A61K31/426;C07C51/09;C07C67/343;C07C69/734;C07C69/736;C07D277/24;C07D333/16;C07D333/56 |
主分类号 |
C07C59/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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