CONTROLLED RELEASE DEPOT FORMULATIONS

摘要

Methods and compositions for systemically or locally administering a beneficialagent to a subject are described, and include, for example, depot gel compositions that can be injected into a desired location and which can provide controlled release of @beneficial agent over a prolonged duration of time. The compositions include a biocompatiNe polymer, a biocompatible solvent having low water miscibility that forms a viscous gel with the polymer and limits water uptake by the implant, and a beneficial agent.