AN OPTIMIZED BILAYERED TABLET DOSAGE FORM WITH TWO ACTIVE ANTIBIOTICS: CLAVULANIC ACID AND CEFPODOXIME

摘要

This invention discloses optimized pharmaceutical formulation for bilayer tablet form comprising at least one antibiotic or a pharmaceutically acceptable salt thereof, and at least one dissolution enhancing agent sufficient to substantially dissolve said one aqueous diluent, binder, disintigrants, Film forming agents, moisture barrier agents. Both ingredient in a single dosages form at same time with high solubility and stability by over coming cross interaction or chemical incompatibilities between two different physical, chemical and physicochemical drug molecules by physical separation, and to enable the development of different drug release profile both in immediate release and immediate release with extended release and promoting patient convenience and compliance.