发明名称 METHOD FOR PRODUCING BENZOPHENONE DERIVATIVE
摘要 Provided are: a compound represented by general formula (I) (wherein R1a and R1b may be the same as or different from each other and independently represent a benzyl group substituted by one to three halogen atoms, wherein, when the number of the halogen atoms is two or three, the halogen atoms may be the same as or different from each other; R2 represents a lower alkyl group which may have a substituent; and R3 represents a lower alkoxycarbonyl group which may have a substituent) or a salt thereof, which is useful in, for example, a method for producing an intermediate for the synthesis of a benzophenone derivative having an anti-tumor activity and the like; a method for producing a benzophenone derivative represented by general formula (III) (wherein R1a, R1b, R2 and R3 are as defined above; R4 represents a lower alkyl group which may have a substituent; and R5 represents an aliphatic heterocyclic alkyl group which may have a substituent) or a salt thereof, the method being characterized by comprising reacting a compound represented by general formula (II) (wherein R4 and R5 are as defined above) or a salt thereof in the presence of an acid; and others.
申请公布号 WO2013002253(A1) 申请公布日期 2013.01.03
申请号 WO2012JP66368 申请日期 2012.06.27
申请人 KYOWA HAKKO KIRIN CO., LTD.;MATSUMURA, TSUTOMU;SAITOH, TOSHIKAZU;TAKEMURA, KAZUNOBU;KOBAYASHI, KENTARO;NITTA, MARIKO;HAGIHARA, KOJI 发明人 MATSUMURA, TSUTOMU;SAITOH, TOSHIKAZU;TAKEMURA, KAZUNOBU;KOBAYASHI, KENTARO;NITTA, MARIKO;HAGIHARA, KOJI
分类号 C07D295/08;C07C69/734 主分类号 C07D295/08
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