摘要 |
<p>Compositions, kits and methods for treating leukemia in a subject (e.g., human) include a first anti-cancer drug consisting of: ?12-prostaglandin J3 or a derivative thereof, or a prostaglandin D receptor (DP) agonist. The compositions may further include a second anti-cancer drug. ?12-prostaglandin J3 is a stable metabolite of omega-3 fatty acid, eicosapentaenoic acid (EPA), and was discovered to have anti-leukemic properties. The compositions, kits and methods may be particularly useful for treating human subjects who are resistant to one or more anti-cancer drugs.</p> |
申请人 |
THE PENN STATE RESEARCH FOUNDATION;PRABHU, KUMBLE, SANDEEP;PAULSON, ROBERT, FRANK;HEGDE, SHAILAJA;KAUSHAL, NAVEEN;GANDHI, UJJAWAL, HITENDRA |
发明人 |
PRABHU, KUMBLE, SANDEEP;PAULSON, ROBERT, FRANK;HEGDE, SHAILAJA;KAUSHAL, NAVEEN;GANDHI, UJJAWAL, HITENDRA |