发明名称 |
Methods for Diagnosing The Malignant Potential of Pancreatic Cystic Lesions |
摘要 |
A method of diagnosing the malignant potential of a pancreatic cystic lesion in a subject including: detecting a glycan alteration in MUC5AC in a sample of pancreatic cystic lesion fluid from a subject, determining whether the glycan alteration is differentially present in the sample, and diagnosing the malignant potential of the pancreatic cystic lesion. A method of diagnosing the malignant potential of a pancreatic cystic lesion in a subject including: (a) detecting a glycan alteration in MUC5AC in a sample of pancreatic cystic lesion fluid from a subject, (b) detecting CA 19-9 in the sample, (c) determining whether the glycan alteration and CA 19-9 are differentially present in the sample, and (d) diagnosing the malignant potential of the pancreatic cystic lesion. Related methods of treatment and kits also are included.
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申请公布号 |
US2013005598(A1) |
申请公布日期 |
2013.01.03 |
申请号 |
US201013519766 |
申请日期 |
2010.12.30 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF MICHIGAN;VAN ANDEL RESEARCH INSTITUTE;HAAB BRIAN B.;SIMEONE DIANE |
发明人 |
HAAB BRIAN B.;SIMEONE DIANE |
分类号 |
G01N33/574;A61B5/153;C40B30/04;C40B40/10 |
主分类号 |
G01N33/574 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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