发明名称 HETERODIMERIZED POLYPEPTIDE
摘要 The present inventors produced a heterodimerized polypeptide having an Fc region that comprises two polypeptides having different amino acid sequences from each other (i.e., a first polypeptide and a second polypeptide), and thus succeeded in the production of a heterodimerized polypeptide containing an Fc region having an improved function compared with that of a homodimer having an Fc region composed only of the first polypeptide or a homodimer having an Fc region composed of the second polypeptide which are conventional techniques.
申请公布号 WO2013002362(A1) 申请公布日期 2013.01.03
申请号 WO2012JP66665 申请日期 2012.06.29
申请人 CHUGAI SEIYAKU KABUSHIKI KAISHA;MIMOTO, FUTA;KURAMOCHI, TAICHI;IGAWA, TOMOYUKI;KAWAZOE, MEIRI;KATADA, HITOSHI;SHIRAIWA, HIROTAKE;KADONO, SHOJIRO 发明人 MIMOTO, FUTA;KURAMOCHI, TAICHI;IGAWA, TOMOYUKI;KAWAZOE, MEIRI;KATADA, HITOSHI;SHIRAIWA, HIROTAKE;KADONO, SHOJIRO
分类号 C12N15/09;A61K39/395;C07K16/28;C07K16/46 主分类号 C12N15/09
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