发明名称 |
Methods for treating interstitial cystitis |
摘要 |
Described herein are methods for treating interstitial cystitis in a subject comprising administering to the subject an effective amount of a compound which is a modified hyaluronan or a pharmaceutically acceptable salt or ester thereof, wherein said hyaluronan or its pharmaceutically acceptable salt or ester comprises at least one sulfate group and the primary C-6 hydroxyl proton of at least one N-acetyl-glucosamine residue is substituted with an unsubstituted alkyl group or fluoroalkyl group.
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申请公布号 |
US8343942(B2) |
申请公布日期 |
2013.01.01 |
申请号 |
US201113069860 |
申请日期 |
2011.03.23 |
申请人 |
UNIVERSITY OF UTAH RESEARCH FOUNDATION;OOTTAMASATHIEN SIAM;JIA WANJIAN;PRESTWICH GLENN D.;MCCOARD LINDSI |
发明人 |
OOTTAMASATHIEN SIAM;JIA WANJIAN;PRESTWICH GLENN D.;MCCOARD LINDSI |
分类号 |
A61K31/728;A61K9/00;A61P27/02;A61P27/04;C08B37/08 |
主分类号 |
A61K31/728 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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