| 发明名称 |
Synthesis process, and crystalline forms of 4-{3-[cis-hexahydrocyclopenta[c]pyrrol-2(1H)-yl]propoxy]benzamide hydrochloride and of free base, pharmaceutical compositions containing them for the treatment of cognitive and psycho-behavioural disorders |
| 摘要 |
<p>The present invention relates to a process for the industrial synthesis of 4-{3-[cis-hexahydrocyclopenta[c]pyrrol-2(1H)-yl]propoxy]benzamide hydrochloride of formula (I):The present invention relates also to crystalline form I of this hydrochloride, to crystalline form of the free base, and also to pharmaceutical compositions containing them for the treatment of cognitive and psycho-behavioural disorders.</p> |
| 申请公布号 |
MD20120049(A2) |
申请公布日期 |
2012.12.31 |
| 申请号 |
MD20120000049 |
申请日期 |
2012.06.07 |
| 申请人 |
LES LABORATOIRES SERVIER |
发明人 |
ROBERT NICOLAS;LERESTIF JEAN-MICHEL;LECOUVE JEAN-PIERRE;GAILLARD MARINA;MEUNIER LOIC;LETELLIER PHILIPPE;BOIRET MATHIEU |
| 分类号 |
C07D209/52;A61K31/085;A61K31/165;A61K31/403;A61P25/00;A61P25/16;A61P25/24;A61P25/28;C07C231/12;C07C233/65;C07C235/44 |
主分类号 |
C07D209/52 |
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