发明名称 NOVEL FORMULATIONS WHICH STABILIZE AND INHIBIT PRECIPITATION OF IMMUNOGENIC COMPOSITIONS
摘要 The present invention addresses an ongoing need in the art to improve the stability of immunogenic compositions such as polysaccharide-protein conjugates and protein immunogens. The invention broadly relates to novel formulations which stabilize and inhibit precipitation of immunogenic compositions. More particularly, the invention described hereinafter, addresses a need in the art for formulations which stabilize and inhibit particulate formation (e.g., aggregation, precipitation) of immunogenic compositions which are processed, developed, formulated, manufactured and/or stored in container means such as fermentors, bioreactors, vials, flasks, bags, syringes, rubber stoppers, tubings and the like.
申请公布号 EA017436(B1) 申请公布日期 2012.12.28
申请号 EA20080070480 申请日期 2007.04.19
申请人 WYETH LLC 发明人 KHANDKE LAKSHMI;CHEN YING;HAN HANYOUNG;SEID ROBERT, CHANCEY, JR.;JIN ZHAOWEI;LOOK JEE, LOON;MALONE RONALD;YANG XUDONG
分类号 A61K47/12;A61K47/48 主分类号 A61K47/12
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