发明名称 |
SMALL MOLECULE COMPOUNDS AS BROAD-SPECTRUM INHIBITORS OF METALLO-BETA-LACTAMASES |
摘要 |
The present invention concerns methods and/or compositions for treatment and/or prevention of bacterial infection wherein the bacteria has at least one metallo-β-lactamase. The bacteria are provided with an inhibitor of the metallo-β-lactamase, for example in conjunction with an antibiotic that targets the bacteria. The bacteria may be a drug-resistant strain or susceptible to becoming a drug-resistant strain. In specific embodiments, the bacteria is Pseudomonas or Acinetobacter spp.
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申请公布号 |
US2012329842(A1) |
申请公布日期 |
2012.12.27 |
申请号 |
US201113332793 |
申请日期 |
2011.12.21 |
申请人 |
SONG YONGCHENG;PALZKILL TIMOTHY;CHEN PINHONG;HORTON LORI |
发明人 |
SONG YONGCHENG;PALZKILL TIMOTHY;CHEN PINHONG;HORTON LORI |
分类号 |
A61K31/426;A61P31/04;C07D277/56;C12N9/99 |
主分类号 |
A61K31/426 |
代理机构 |
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主权项 |
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地址 |
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