发明名称 |
METHOD FOR PREPARING MESO-2,3-BUTANEDIOL |
摘要 |
The present invention relates to a method for preparing meso-2,3-butanediol. More particularly, the present invention relates to colon bacillus for overexpressing meso-2,3-butaediol, which is cotransformed to an expression vector including at least one nucleotide SEQ ID selected from the group consisting of the following nucleotide SEQ IDs: (a) nucleotide-coding acetoin reductase having an amino acid sequence described in SEQ ID 5 of a sequence listing; (b) nucleotide-coding acetolactate decarboxylase; and (c) nucleotide-coding alcohol dehydrogenase. The cotransformed colon bacillus of the present invention can produce 2,3-butanediol, which could not be obtained from wild species. Therefore, it is possible to biosynthesize a large amount of meso-2,3-butanediol through the biosynthesis path expression of meso-2,3-butanediol from glucose, and through metabolic flux change by means of the insertion of the genes of other species. |
申请公布号 |
WO2012124890(A3) |
申请公布日期 |
2012.12.27 |
申请号 |
WO2012KR00436 |
申请日期 |
2012.01.18 |
申请人 |
INDUSTRY-UNIVERSITY COOPERATION FOUNDATION SOGANGUNIVERSITY;LEE, JIN WON;LEE, SOO JIN;KIM, BO-RIM;CHOI, WOO JOO |
发明人 |
LEE, JIN WON;LEE, SOO JIN;KIM, BO-RIM;CHOI, WOO JOO |
分类号 |
C12N1/21;C12N15/53;C12N15/60;C12N15/70;C12P7/16 |
主分类号 |
C12N1/21 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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