| 摘要 |
FIELD: chemistry.SUBSTANCE: disclosed is a method of producing a compound of formula(I), where N equals 0, and values of substitutes R, Rare given in claim 1, which involves: (i) esterification of a compound of formula(V) with an alcohol of formula, where m and m' are independently equal to 0 or 1; under the condition that both are not equal to 0 at the same time and values of A are given in claim 1, to obtain a compound of formula(III); (ii) reaction of the compound of formula (III) and a compound of formula(IV) to obtain a compound of formula(II); and (iii) reaction of the compound of formula (II) with L-CH-C?CH, wherein L is a leaving group, to form a compound of formula (I); intermediate compounds of formula (II), formula (III) and formula(XII) are also disclosed.EFFECT: improved method.15 cl, 19 ex, 1 dwg |
