摘要 |
Provided are anti-human a-synuclein-specific binding molecules, e.g., antibodies or antiben-binding fragments, variants or derivatives thereof, as methods related thereto. Further provided are anti-human a-synuclein binding molecules which bind to specific N-terminal and C-terminal epitopes on human a-synuclein. The binding molecules described herein can be used in pharmaceutical and diagnostic compositions for a-synuclein targeted immunotherapy and diagnosis, respectively. |
申请人 |
BIOGEN IDEC INTERNATIONAL NEUROSCIENCE GMBH;UNIVERSITY OF ZURICH;WEIHOFEN, ANDREAS;GRIMM, JAN;HOCK, CHRISTOPH;NITSCH, ROGER;SU, LIHE;WEINREB, PAUL |
发明人 |
WEIHOFEN, ANDREAS;GRIMM, JAN;HOCK, CHRISTOPH;NITSCH, ROGER;SU, LIHE;WEINREB, PAUL |