发明名称 |
ANTI-ALPHA SYNUCLEIN BINDING MOLECULES |
摘要 |
Provided are anti-human a-synuclein-specific binding molecules, e.g., antibodies or antiben-binding fragments, variants or derivatives thereof, as methods related thereto. Further provided are anti-human a-synuclein binding molecules which bind to specific N-terminal and C-terminal epitopes on human a-synuclein. The binding molecules described herein can be used in pharmaceutical and diagnostic compositions for a-synuclein targeted immunotherapy and diagnosis, respectively. |
申请公布号 |
CA2839563(A1) |
申请公布日期 |
2012.12.27 |
申请号 |
CA20122839563 |
申请日期 |
2012.06.22 |
申请人 |
BIOGEN IDEC INTERNATIONAL NEUROSCIENCE GMBH;UNIVERSITY OF ZURICH |
发明人 |
WEIHOFEN, ANDREAS;GRIMM, JAN;HOCK, CHRISTOPH;NITSCH, ROGER;SU, LIHE;WEINREB, PAUL |
分类号 |
A61K39/395;A61K47/48;C07K14/47;C07K16/18;C07K16/46;C12N15/13;G01N33/53 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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