RIMFAMPICIN ANALOGUE USEFUL FOR INFECTION IMAGING

摘要

The present invention provides radiolabelled RIF derivatives that are suitable for in vivo imaging of bacterial infection. The in vivo imaging agent of the invention is preferably provided as a radiopharmaceutical composition, which forms a further aspect of the invention. Also provided by the present invention is a precursor compound useful in the preparation of the in vivo imaging agent of the invention, a method for the preparation of the in vivo imaging agent of the invention comprising reaction of the precursor compound with a suitable source of the desired radiolabel, and methods for the use of the in vivo imaging compound.