| 发明名称 |
Immunoconjugates with an Intracellularly-Cleavable Linkage |
| 摘要 |
The invention relates to therapeutic conjugates with improved ability to target various cancer cells containing a targeting moiety and a therapeutic moiety. The targeting and therapeutic moieties are linked via an acid cleavable linkage that increases therapeutic efficacy of the immunoconjugate.
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| 申请公布号 |
US2012328634(A1) |
申请公布日期 |
2012.12.27 |
| 申请号 |
US201213586281 |
申请日期 |
2012.08.15 |
| 申请人 |
IMMUNOMEDICS, INC. |
发明人 |
GOVINDAN SERENGULAM V. |
| 分类号 |
A61K39/395;A61K47/48;A61P3/10;A61P13/12;A61P17/00;A61P25/00;A61P35/00;A61P37/06 |
主分类号 |
A61K39/395 |
| 代理机构 |
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代理人 |
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