发明名称 USE OF YSCF, TRUNCATED YSCF AND YSCF HOMOLOGS AS ADJUVANTS
摘要 An antigenic composition comprising an antigen and an effective adjuvant, the adjuvant comprising isolated or recombinant YscF, a YscF fragment, trYscF, or homologs thereof. A method of inducing an enhanced immune response comprising administering an antigen and an effective adjuvant comprising isolated or recombinant YscF, a YscF fragment, trYscF, or homologs thereof. An antigenic composition produced by a process comprising providing a host cell with an expression vector containing a nucleotide sequence encoding YscF, a YscF fragment, trYscF, or YscF homolog capable of acting as an adjuvant; expressing the nucleotide sequence in the host cell to produce the protein; and mixing the collected protein with a suitable excipient.
申请公布号 WO2012178078(A2) 申请公布日期 2012.12.27
申请号 WO2012US43838 申请日期 2012.06.22
申请人 UNIVERSITY OF NORTH DAKOTA;NILLES, MATTHEW 发明人 NILLES, MATTHEW
分类号 A61K39/39;A61K38/16;A61K38/17;A61K39/38;A61P31/00;A61P37/00 主分类号 A61K39/39
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